PRP (platelet-rich plasma) in research and healthcare I
An info series on Dr. Ursus Lüthi and Dr. Peter Schnorr
Dr. Ursus Lüthi and Dr. Peter Schnorr regularly appear as participants and as speakers at international conferences where they deal closely with the latest research studies and results from regenerative medicine. Our new PRP in research and healthcare series rounds up the most important news and views from the field.
PROM (patient-reported outcome measures) scores
Current studies have shown that “old” evaluation criteria (“scores”) are not enough to establish the extensive, biologically sound benefits of PRP (platelet-rich plasma) treatment. PROM (patient-reported outcome measures) scores also provide important additional insights especially regarding the high level of application safety, significant relief from pain and increase in performance and endurance.
Treatment standardisation and product standards
Standardising treatment has been given great importance as it allows documented comparability between treatments towards further improvements in patient outcomes from the resulting data.
Documenting the PRP used is especially important, including laboratory documentation; this is standard procedure in every treatment at FIRST. Apart from that, we at FIRST select products that have proven their worth in clinical settings and also have a broad range of scientific data to back them up.
Studies demonstrate treatment safety and efficacy
None of the numerous studies available have so far reported any negative or dangerous effects of PRPs – a highly favourable point well worth emphasising. The following treatment areas are seeing increasing benefits from favourable developments with high levels of statistical validity in research findings:
- Osteoarthritis treatment on the knee and hip joint
Chen, P., Huang, L., Ma, Y., Zhang, D., Zhang, X., & Zhou, J. et al. (2019). Intra-articular platelet-rich plasma injection for knee osteoarthritis: a summary of meta-analyses. Journal Of Orthopaedic Surgery And Research, 14(1). doi: 10.1186/s13018-019-1363-y
Sánchez, M., Fiz, N., Guadilla, J., Padilla, S., Anitua, E., Sánchez, P., & Delgado, D. (2014). Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis. Arthroscopy Techniques, 3(6), e713-e717. doi: 10.1016/j.eats.2014.09.006
- Shoulder (rotator cuff)
Jancuska, J., Matthews, J., Miller, T., Kluczynski, M., & Bisson, L. (2018). A Systematic Summary of Systematic Reviews on the Topic of the Rotator Cuff. Orthopaedic Journal Of Sports Medicine, 6(9), 232596711879789. doi: 10.1177/2325967118797891
- Tennis elbow
Tang, S., Wang, X., Wu, P., Wu, P., Yang, J., & Du, Z. et al. (2020). Platelet‐Rich Plasma Vs Autologous Blood Vs Corticosteroid Injections in the Treatment of Lateral Epicondylitis: A Systematic Review, Pairwise and Network Meta‐Analysis of Randomized Controlled Trials. PM&R, 12(4), 397-409. doi: 10.1002/pmrj.12287
- Tendon attachment at the trochanter and hip bone
Fitzpatrick, J., Bulsara, M., O’Donnell, J., & Zheng, M. (2019). Leucocyte-Rich Platelet-Rich Plasma Treatment of Gluteus Medius and Minimus Tendinopathy: A Double-Blind Randomized Controlled Trial With 2-Year Follow-up. The American Journal Of Sports Medicine, 47(5), 1130-1137. doi: 10.1177/0363546519826969
- Achilles tendon
The efficacy of PRP has not yet been demonstrated to a sufficient level of scientific rigour; however, we have achieved highly favourable outcomes in this area using our own treatment method.
Read about the new treatment options PRP provides for back pain in the next PRP in research and healthcare.